A research team at Harvard University has developed 2 new wound dressings that advance healing without depending on cells, growth factors, or even artificial scaffolds. Rather, the natural proteins that exist in human fetus cells and soy are prepared to accelerate the natural healing processes of the body, comprising executing techniques that only fetal tissue is skilled of.
One dressing holds fibrous fibronectin, which is a protein that structures the extracellular matrix and holds the cells collectively that are developing into new tissues. It has been researched owing to its function in scarless healing in the fetuses’ early growth, but producing it has been complicated. The Harvard team, looking forward to make dressings that would assist with battleground injuries, utilized a tool called Rotary Jet-Spinning to develop fibrous fibronectin and subsequently make it into big bandages and dressings.
The fibrous fibronectin functions to direct development by magnetizing the preferred cells that are implicated in the process of healing. The material is then soaked up by the body. As per the announcement by Harvard, in in-vivo assessments, the dressing composed of fibrous fibronectin showed “84% tissue reinstatement in 20 Days, in comparison to 55.6% reinstatement in injuries treated with a customary dressing.” Moreover, the wounds cured with the assistance of the new bandage had an almost normal skin thickness, its makeup was fit, and it even developed new hair.
The other dressing consists of a soy-based nanofiber, which has estrogen-like particles and other bioactive constituents that assist to produce and encourage cellular development. Estrogen has been eminent as serving pregnant women cure wounds quicker. The soy nanofiber is gyrated in the same device that fibrous fibronectin was generated and it had analogous outcomes. As per Harvard, this novel dressing “showed a 72% rise in curing over wounds without dressing and a 21% rise in curing over wounds dressed lacking soy protein.”